John Cole, PhD

John Cole

Speaker Titles and Affiliations
Co-Founder, SimBioSys, Inc.

Speaker Degrees and Certifications: PhD
Speaker Web Page: SimBioSys Website
Educational Program: TiMe

Simbiosys Inc. is developing a software environment that enables computational biologists to integrate -omics and imaging data in order to build unified 3D models of cancers and their surrounding tissues with the hope that it aids in the discovery of new drug targets, and investigate why some drugs fail and others succeed.

You wouldn’t put a brain cell in a petri dish and expect it to think, and you wouldn’t put a lung cell in a liver and expect it to help filter blood.

Why? Because cellular function depends on both the cell’s internal state (what genes are expressed, or if there are any mutations, etc.), and its broader context (what other cells and chemicals are around). In cancers, both of these are disrupted, and drug-development research focused to heavily on the internal cellular state has proven to be expensive and prone to high failure rates. Simbiosys Inc. is developing a software environment that enables computational biologists to integrate -omics and imaging data in order to build unified 3D models of cancers and their surrounding tissues with the hope that it aids in the discovery of new drug targets, and investigate why some drugs fail and others succeed.

Speaker Date
03-29-2018