Author: amyliles@illinois.edu

2018-04-17 The TiMe Cohort hosted the second-annual Tissue Microenvironment (TiMe) Day Symposium and Poster Session on April 13, 2018 at the Beckman Institute for Advanced Science and Technology. There were over seventy attendees from 14 departments across campus including guests from industry. The symposium explored different aspects of the tissue microenvironment through six faculty research […]

2018-04-06 Sisi He was selected for an oral presentation at ENDO 2018. She was awarded Endocrine Society Outstanding Abstract Award & EndoCareers Early Career Forum Travel Award. Abstract: The poor prognosis of ovarian cancer patients (5-year survival is less than 50%) is due, in part, to progressive development of resistance to chemotherapy. Overexpression of the […]

2018-04-06 Authors: Ruibo Wang, Kaimin Cai, Hua Wang, Chen Yin and Jianjun Cheng Abstract: In this work, we report selection of covalent linker on anomeric position of N-azidoacetylmannosamine (ManNAz) for caging its metabolic process. We synthesized DT-diaphorase responsive metabolic precursor HQ-NN-AAM using the optimized linker. The caged metabolite showed responsiveness to DT-diaphorase in vitro, resulting […]

2018-03-08 Authors: Jee-Wei Emily Chen, Jan Lumibao, Audrey Blazek, H. Rex Gaskins and Brendan Harley* Abstract: Glioblastoma (GBM) is the most common, aggressive, and deadly form of adult brain cancer, and is associated with a short survival rate (median 12–15 months, 5+ year less than 5%). The complex tumor microenvironment includes matrix transitions at the […]

Originally published on 2018-02-22 The Tissue Microenvironment class was privileged to spend an hour and a half talking with Dr. Oguzhan Alagoz from the University of Wisconsin-Madison. Dr. Alagoz came in from Wisconsin to speak to the ISE Graduate Seminar students, but graciously took time out to speak to the TiMe students about his experience […]

2017-11-09 Joanne Li, one of our Tissue Microenvironment students, recently published a paper on topically treating diabetic wounds with microscopy. Read the full paper here and see the abstract below. Impaired skin wound healing is a significant comorbid condition of diabetes that is caused by poor microcirculation, among other factors. Studies have shown that angiogenesis, […]

2017-10-16 Sisi He and Dr. Erik Nelson recently published a paper on estrogen receptors. Abstract: Estrogen receptors (ERs) mediate the actions of the steroidal estrogens, and are important for the regulation of several physiological and pathophysiological processes, including reproduction, bone physiology, cardiovascular physiology and breast cancer. The unique pharmacology of the ERs allows for certain […]

Orignally published on: 2017-05-18 Our inaugural Tissue Microenvironment (TiMe) Training Program Symposium hosted on Monday, May 15, 2107 was a great success! Each of the TiMe students presented a summary of their research projects, followed by presentations from members of the External Advisory Board, Dr. David Beebe (University of Wisconsin Madison), Dr. Peter So (MIT), […]

Orignally published on 2017-05-18 Our inaugural Tissue Microenvironment (TiMe) Training Program Symposium hosted on Monday, May 15, 2107 was a great success! Each of the TiMe students presented a summary of their research projects, followed by presentations from members of the External Advisory Board, Dr. David Beebe (University of Wisconsin Madison), Dr. Peter So (MIT), […]

Paloma Pearson 2017-05-18 The inaugural Tissue Microenvironment (TiMe) Training Program Symposium, held on Monday, May 15, 2017, was a great success. Each of the TiMe students presented a summary of their research projects, followed by presentations from members of the External Advisory Board: Dr. David Beebe (University of Wisconsin-Madison), Dr. Peter So (MIT), and Dr. […]