Tissue Microenvironment (TiMe) Program Scholars organized and hosted the third-annual TiMe Symposium on April 26, 2019, at the Beckman Institute for Advanced Science and Technology. Over 90 participants across 15 University of Illinois campus departments attended the Symposium. Dennis Discher, Professor of Chemical and Biological Engineering from the University of Pennsylvania, served as keynote speaker, and Rashid Bashir, Professor of Engineering and Dean of the Grainger College of Engineering provided the lunchtime talk. In addition, there were four plenary talks by Illinois faculty members and the TiMe scholars presented three-minute lightning talks to highlight their research. Best poster awards were given to Luke Akin (Chemistry), Anuj Yadav (Chemistry), and Mai Ngo (Chemical and Biomolecular Engineering).